On the pharmacological profile of SQ 29,852 (SQ), a novel angiotensin converting enzyme (ACE) inhibitor
نویسندگان
چکیده
منابع مشابه
Attenuation of nephrotoxic acute renal failure in the dog with angiotensin-converting enzyme inhibitor (SQ-20,881).
Angiotensin-converting enzyme inhibitor was used in dogs with uranyl nitrate-induced acute renal failure to evaluate (1) a possible protective effect of angiotensin blockade and (2)the role of angiotensin II in the generation of renal failure in this model. Angiotensin-converting enzyme inhibitor treatment attenuated the fall in glomerular filtration rate and renal blood flow during the first 6...
متن کاملBeneficial Action of a New Angiotensin- Converting Enzyme Inhibitor (SQ 14,225) in Hemorrhagic Shock in Cats
preganglionic motoneurones in the medulla of the cat. J Physiol (Lond) 258: 187-204, 1976 11. Curtis DR, Eccles JC: Synaptic action during and after repetitive stimulation. J Physiol (Lond) 150: 374-398, 1959 12. Auerbach AA: Transmitter release at chemical synapses. In Structure and Function of Synapses, edited by GC Pappas, DP Purpura. New York, Raven Press, 1972, pp 137-159 13. Dennis MJ, Ha...
متن کاملBeneficial action of new angiotensin-converting enzyme inhibitor (SQ 14,225) in hemorrhagic shock in cats.
preganglionic motoneurones in the medulla of the cat. J Physiol (Lond) 258: 187-204, 1976 11. Curtis DR, Eccles JC: Synaptic action during and after repetitive stimulation. J Physiol (Lond) 150: 374-398, 1959 12. Auerbach AA: Transmitter release at chemical synapses. In Structure and Function of Synapses, edited by GC Pappas, DP Purpura. New York, Raven Press, 1972, pp 137-159 13. Dennis MJ, Ha...
متن کاملEffect of angiotensin-converting enzyme inhibitor (SQ 20881) on the plasma concentration of angiotensin I, angiotensin II, and arginine vasopressin in the dog during hemorrhagic shock.
The effect of an angiotensin-converting enzyme inhibitor on the circulating levels of angiotensin I, angiotensin II, and arginine vasopressin was studied in dogs subjected to hypotensive hemorrhagic shock. In dogs subjected to hemorrhage but not given the inhibitor, angiotensin II rose 20-fold (from 69 to 1,343 pg/ml of plasma), whereas in dogs subjected to hemorrhage but pretreated with the in...
متن کاملP23: The Effects of Captopril, as Angiotensin Converting Enzyme Inhibitor, on LPS-Induced Systemic Inflammation
It has been shown that the renin-angiotensin system (RAS) plays key roles in the inflammation process. Imbalance in the oxidant-antioxidant system is one of the major causes of inflammation. In the present study, the effects of captopril on total and differential WBC, oxidative stress in systemic inflammation produced by lipopolysaccharide (LPS) were investigated. The rats were divided to: cont...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1989
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)56475-7